Over the past year, conversations about GLP-1 for weight loss have moved from medical journals to dinner tables and social media feeds. More recently, the buzz is around a new trend: “micro-dosing” these medications.
But like any new trend, it’s important to tell apart what is promising from what needs careful medical attention.
As a surgeon who helps patients achieve their body goals safely and sustainably, I’ve seen firsthand how curiosity about GLP-1s is growing. Many people are intrigued by the idea of using smaller doses to ease side effects or maintain results after weight loss.
Here’s what you should understand about micro-dosing GLP-1s and why physician guidance remains essential.
The term GLP-1 refers to the hormone glucagon-like peptide-1, which is naturally produced in the gut after meals and helps regulate appetite, digestion, and insulin release. Medications called GLP-1 receptor agonists (GLP-1 RAs) mimic this hormone’s effect. Some major ones include semaglutide and tirzepatide.
These medications were initially developed for type 2 diabetes, and more recently have been approved for weight management, because they can reduce appetite, slow gastric emptying, and improve insulin sensitivity.
In this context, microdosing means taking a smaller-than-the-usual prescribed dose of GLP-1 medications. For example, instead of starting with the manufacturer’s recommended start dose for weight-loss or diabetes, a person might take a fraction of that dose.
Some providers may choose a lower‐than‐standard therapeutic dose. Using compounded medication to customize dosing for each patient.
Potential fit:
Likely not a fit:
If you’re exploring this with a healthcare provider, here are some practical points and considerations:
Microdosing GLP-1 medications is an emerging trend, driven by desire for fewer side-effects, maintenance dosing, lower cost, and more gradual adoption of treatment. However, because the evidence base is limited, it must be approached with caution, professional guidance, and realistic expectations.
If you’re considering a microdose strategy, I strongly recommend discussing the option with your physician; exploring the full therapy (standard dose) vs. micro-dose strategy, reviewing risks and benefits in your personal health context, and making a customized plan that includes monitoring and lifestyle integration.
Your weight loss journey should fit you.
At Impressions Face and Body, Dr. Eric W. Anderson and aesthetic specialist Selika Gutierrez-Borst, MS, RN, are introducing a next-generation, physician-led weight loss program that goes beyond prescriptions.
By combining advanced GLP-1 treatments with personalized aesthetic care, this program is designed to help you look and feel your best throughout every stage of your transformation.
To support lasting results, Impressions has partnered with Revolution Physical Therapy, creating a full-circle approach that integrates:
Together, this approach provides both the medical foundation and lifestyle tools needed for real, lasting change.
If you’re considering GLP-1 therapy or want to explore how it can complement your body goals, our team can help you design a plan that aligns with your health, lifestyle, and aesthetic vision. Ready to take the right step?