Demystifying “GLP Face”:
What Happens to Your Face When
You Lose Weight Fast?
Weight loss medications like Ozempic (semaglutide), Wegovy, and Mounjaro (tirzepatide) have taken center stage in recent weight loss programs. These GLP-1 (glucagon-like peptide 1) receptor agonists are changing lives by helping people lose significant weight. But with those transformations can come some unexpected changes, especially in the face.
You might be familiar with the term “GLP Face”, which is also referred to as “GLP-1 face”, “Ozempic face” or “semaglutide face” (all used interchangeably).
GLP Face refers to the reduction in facial volume and firmness of the skin. This phenomenon happens with rapid weight loss from GLP-1 agonist medications. Sunken cheeks, sagging skin, more visible fine lines and wrinkles can become more pronounced, especially if you are over 40. That’s because as we get older, our natural collagen production slows down, making skin less firm and resilient. Add rapid weight loss into the mix, and the changes can feel even more dramatic. When facial fat (the good type!) diminishes rapidly, the skin may not have sufficient time to recover its elasticity.
The effects of GLP-1 weight loss on facial aging go beyond appearances — they involve underlying changes beneath the surface. Our faces are made up of multiple fat pads that give structure and fullness. When weight is lost too quickly, those deep and superficial fat compartments shrink unevenly. This may result in the face appearing sunken, fatigued, or older than you feel.
Imagine it as letting the air out of a balloon — you end up with excess skin that lacks the previous support it once had.
These GLP-1 Face effects may feel frustrating, but they’re treatable.
At Impressions Face + Body, we offer a range of cutting-edge solutions to restore volume, tighten skin, and bring back your glow:
Dermal Fillers: Products like Juvéderm and Restylane replenish lost volume in areas like the cheeks, temples, and smile lines — instantly lifting and smoothing.
Biostimulators: Sculptra and Radiesse work over some time to stimulate your body’s collagen production, delivering natural-looking, long-term results.
Skin Tightening Treatments: Technologies like Ultherapy and RF microneedling (radiofrequency) tighten loose skin by encouraging collagen remodeling.
Fat Grafting: For a more permanent, natural option, we can use your own fat to restore facial fullness— essentially recycling it from one area of the body to enhance another.
Medical-Grade Skincare + Lifestyle Support: With the right skincare—think retinol, peptides, hyaluronic acid—and a nutrient-rich diet, your skin can maintain its elasticity and stay healthy from the inside out.
Sagging Skin: Without the support of underlying fat, the skin can sag, giving the face a more aged appearance.
Wrinkles: The reduction in facial volume can exacerbate the appearance of facial aging and wrinkles, making them more pronounced.
Hollow Cheeks and Eyes: The loss of fat in the cheeks and around the eyes can create a hollow look, diminishing the youthful fullness of the face.
If you're considering GLP-1 medications or are in the early stages of weight loss, there are proactive steps you can take:
GLP-1 therapies are here to stay, and they’re helping people feel better in their bodies.
But you don't have to compromise your overall look. The key is taking a holistic approach: one that supports your weight loss goals and your facial rejuvenation.
At Impressions Face + Body, we are here to help you through the process. Whether you’re just beginning your GLP-1 journey or looking to restore facial volume after major weight loss, we’ll create a custom treatment plan tailored to your goals.
You have worked hard on your weight loss journey. Now, let’s focus on how you feel in your body. Book your consultation today.